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Tag: Susvimo

Can we really put an implant inside the eye to deliver drugs to treat eye diseases?

TeachableMedicalNews article 06152022

Teachable moment in classrooms:

  1. cellular basis of life chapter – diffusion as a means of molecular movement
  2. special senses chapter – the photoreceptors rods and cones are in the retina
  3. special senses chapter – liquid-filled chambers of the eye
  4. special senses chapter – sclera, the white of the eye, is the toughest, outer layer

Can we put an implant inside the eye to deliver drugs to treat eye diseases?

The news item:  Recently a report appeared about a drug, Susvimo, that reverses blindness:

New technology helps Georgetown veteran restore his eyesight

If you’re living with blurry vision, there’s a chance a new device can help you get your eyesight back without frequent visits to the doctor. The newly FDA-approved Susvimo implant helped one Georgetown veteran preserve his vision after being diagnosed with wet age-related macular degeneration.

The article states that AMD (wet, age-related macular degeneration) is the leading cause of blindness over the age 60, that this disorder is caused by growth and scarring of blood vessels under the retina, and that drug-delivery through an implant has restored vision in 90% of the treated individuals.

So, Why Do I Care??  Eye diseases can rob people of their vision. Many of such diseases are treated by injection of a drug into the eye. It is estimated that there are over 10 million such injections per year in the USA. Because chronic eye disorders require several injections into the same eye, it is worth exploring alternative delivery systems for long-term administration of drugs.

Plain English, Please!!!   First, let’s review the action of Susvimo, the drug we will use as an example to learn about implants inside the eye. In a previous post of Teachable Medical News (TMN 05252022), we described the action of the drug Susvimo. Here is a brief summary:  Normally the light-sensing cell in the

How does drug injection into the eye save people from blindness?

TeachableMedicalNews article 05252022

Teachable moment in classrooms:

  1. special senses chapter – location of macula lutea in the retina of the eye
  2. special senses chapter – the photoreceptors rods and cones are in the retina
  3. hemodynamics chapter – capillaries are the thinnest blood vessels
  4. hemodynamics chapter – endothelial cell location in capillaries

The news item:  Recently a report appeared about a drug that restores eyesight:

New technology helps Georgetown veteran restore his eyesight

If you’re living with blurry vision, there’s a chance a new device can help you get your eyesight back without frequent visits to the doctor. The newly FDA-approved Susvimo implant helped one Georgetown veteran preserve his vision after being diagnosed with wet age-related macular degeneration.

The article states that AMD (wet, age-related macular degeneration) is the leading cause of blindness over the age 60, that this disorder is caused by growth and scarring of blood vessels under the retina, and that the drug-delivery implant has restored vision in 90% of the treated individuals.

So, Why Do I Care??  Blindness is a condition where a significant part of the eyesight is lost, and such loss has a severe negative impact on people’s lives. In the USA alone there are about a million patients with wet age-related macular degeneration, and without treatment most of them will go blind.

Plain English, Please!!!   First, let’s talk about how the structure called macula plays a role in our vision. When we say we see something, the image of that something has to be turned into a nerve impulse so

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