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Tag: endocytosis

In what possible way could chloroquine defeat the mighty COVID 19 disease?

TeachableMedicalNews article 03202020

Teachable moment in classrooms:

  1. cellular basis of life chapter – receptor mediated endocytosis
  2. cellular basis of life chapter – fusion of endosome with lysosome
  3. cellular basis of life chapter – enzymes inside the lysosome require low pH
  4. microbiology – coronaviruses receptors on cell membranes
  5. microbiology – coronaviruses and their release into the cytoplasm

The news item:  A possible treatment of COVID 19 patients made the news recently:

Chloroquine, an old malaria drug, may help treat novel coronavirus, doctors say

According to early research, an old malaria drug called chloroquine might also work for the new coronavirus.

The article mentions the drug chloroquine, and that it blocks the attachment of the virus to cultured cells.  This latter point is inaccurate, so read on to find out the truth.

So, Why Do I Care??  Have you been living under a rock in the last two

Can an ancient disease cancel a Phish concert?

TeachableMedicalNews article 03052020

Teachable moment in classrooms:

  1. cellular basis of life chapter – endocytosis as cellular transport
  2. immune system chapter – phagocytosis by the cells of the innate immune system
  3. immune system chapter – activation of the B cells by macrophages in the adaptive immune system
  4. immune system chapter – antibodies speed up phagocytosis of invading microbes
  5. microbiology —  pathology of Yersinia pestis bacterium

The news item:  Recently the disease called plague was reported to disrupt camping and other preparation for a Phish concert in Denver:

Plague-ridden prairie dogs force cancellation of Phish camping event

This is probably not what Phish had in mind when they wrote their 1994 single, “Down with Disease.” Self-proclaimed “Phans” of the legendary jam band are singing the blues a…

The article mentioned that prairie dogs were infected with the plague, and there was concern that the plague would be passed on to concert goers.

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